Chromogranin B in Heart Failure

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منابع مشابه

Chromogranin A in heart failure.

Since the initial demonstration of increased circulating norepinephrine in patients with chronic heart failure, a large number of investigations on neuroendocrine activation in heart failure have followed. It is now clear that persistent activation of neuroendocrine systems, notably the adrenergic system and the renin–angiotensin system is maladaptive in heart failure (reviewed in). In this iss...

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Chromogranin B in Heart Failure: A Putative Cardiac Biomarker Expressed in the Failing Myocardium Running Title: Chromogranin B in Heart Failure

Background: Chromogranin B (CgB) is a member of the granin protein family. As CgB is often co-localized with chromogranin A (CgA), a recently discovered cardiac biomarker, we hypothesized that CgB is regulated during heart failure (HF) development. Methods and Results: CgB regulation was investigated in patients with chronic HF and in a post-myocardial infarction (MI) HF mouse model. Animals we...

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Chromogranin B in heart failure: a putative cardiac biomarker expressed in the failing myocardium.

BACKGROUND Chromogranin B (CgB) is a member of the granin protein family. Because CgB is often colocalized with chromogranin A (CgA), a recently discovered cardiac biomarker, we hypothesized that CgB is regulated during heart failure (HF) development. METHODS AND RESULTS CgB regulation was investigated in patients with chronic HF and in a post-myocardial infarction HF mouse model. Animals wer...

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Chromogranin A in heart failure; a novel neurohumoral factor and a predictor for mortality.

BACKGROUND In chronic heart failure, several hormonal systems are activated with diagnostic and prognostic implications. We tested the hypotheses that serum Chromogranin-A (CgA) -- a 49 kDa acid protein present in the secretor granules of neuroendocrine cells -- is increased in chronic heart failure and that CgA levels are a predictive factor for mortality. METHOD AND RESULTS In 160 patients ...

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Food Insecurity Status in Heart Failure Patients in Iranian Population

Background: We were conducted this study to assess the prevalence of food insecurity in heart failure patients households and the relationship between food security and some variables in this households. Methods: In this cross sectional study, a total of 300 heart failure patients' households were studied in Imam Reza hospital of Mashhad. The Iranian version of household food insecurity access ...

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ژورنال

عنوان ژورنال: Circulation: Heart Failure

سال: 2010

ISSN: 1941-3289,1941-3297

DOI: 10.1161/circheartfailure.109.867747